NCALD (C-term) Rabbit Polyclonal Antibody

CAT#: AP52821PU-N

NCALD (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of NCALD Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). This demonstrates the NCALD antibody detected the NCALD protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human NCALD
• Specificity: This antibody recognizes Human and Mouse NCALD (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens neurocalcin delta (NCALD), transcript variant 1
• Database Link:
  Entrez Gene 83988 Human
  UniProt ID P61601
• Background: NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
• Synonyms: Neurocalcin-delta
• Note: Molecular Weight: 22245 Da