MRAP (N-term) Rabbit Polyclonal Antibody

CAT#: AP52742PU-N

MRAP (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MRAP (arrow) in 293 cell line lysates (35ug/lane) using MRAP antibody. (N-term).

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  Immunohistochemistry analysis in breast carcinoma (Formalin-fixed, Paraffin-embedded) using MRAP antibody. (N-term), followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated.

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  Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram) using MRAP antibody. (N-term), followed by FITC-conjugated goat-anti-rabbit secondary antibodies.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: Flow cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin sections: 1/50-1/100.
  Western blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 14-44aa) of human MRAP.
• Specificity: This antibody recognizes MRAP at N-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch. <br />

• Gene Name: melanocortin 2 receptor accessory protein
• Database Link:
  Entrez Gene 56246 Human
  UniProt ID Q8TCY5
• Background: MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.
• Synonyms: Melanocortin-2 receptor accessory protein, C21orf61, FALP
• Note: Molecular Weight: 19136 Da

Reference Data

• Protein Families: Transmembrane