MPP1 (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | FC, IHC, WB |
---|---|
Recommended Dilution | Flow cytometry: 1/10-1/50. Immunohistochemistry on Paraffin sections: 1/50-1/100. Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000. |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated - corresponding to the central region ( between 304-331aa) of human MPP1. |
Specificity | This antibody recognizes human MPP1. |
Buffer | PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | membrane palmitoylated protein 1 |
Database Link | |
Background | This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | p55, DXS552E, EMP55 |
Note | Molecular Weight: 52296 Da |
Reference Data | |
Protein Families | Druggable Genome |
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