CRSP7 (MED26) (Center) Rabbit Polyclonal Antibody

CAT#: AP52654PU-N

CRSP7 (MED26) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MED26 Antibody (Center) in HepG2 cell line lysates (35ug/lane). This demonstrates the MED26 antibody detected the MED26 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 190-220 amino acids from the Central region of human MED26
• Specificity: This antibody recognizes Human MED26 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: mediator complex subunit 26
• Database Link:
  Entrez Gene 9441 Human
  UniProt ID O95402
• Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
• Synonyms: ARC70, CRSP7, Mediator complex 26, CRSP complex subunit 7
• Note: Molecular Weight: 65446 Da

Reference Data

• Protein Families: Druggable Genome