S2P (MBTPS2) (N-term) Rabbit Polyclonal Antibody

SKU AP52627PU-N

S2P (MBTPS2) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500.; Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human MBTPS2
• Specificity: This antibody recognizes Human MBTPS2 (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: membrane bound transcription factor peptidase, site 2
• Database Link:
  O43462
• Background: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
• Synonyms: Site-2 protease, S2P endopeptidas, S2P
• Note: Molecular Weight: 57444 Da

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane