MAFA (C-term) Rabbit Polyclonal Antibody

CAT#: AP52583PU-N

MAFA (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MAFA Antibody (C-term) in K562 cell line lysates (35ug/lane). This demonstrates the MAFA antibody detected the MAFA protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 285-315 amino acids from the C-terminal region of human MAFA
• Specificity: This antibody recognizes Human MAFA (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: MAF bZIP transcription factor A
• Database Link:
  Entrez Gene 389692 Human
  UniProt ID Q8NHW3
• Background:
  MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).
• Synonyms: Transcription factor MafA
• Note: Molecular Weight: 36982 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Maturity onset diabetes of the young, Type II diabetes mellitus