MAFA (Center) Rabbit Polyclonal Antibody

CAT#: AP52582PU-N

MAFA (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of MAFA Antibody (Center) in mouse spleen tissue lysates (35ug/lane). MAFA (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 209~238 amino acids from the Central region of Human MAFA.
• Specificity: This antibody recognizes Human and Mouse MAFA (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: MAF bZIP transcription factor A
• Database Link:
  Entrez Gene 378435 MouseEntrez Gene 389692 Human
  UniProt ID Q8NHW3
• Background:
  MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.
• Synonyms: Transcription factor MafA
• Note: Molecular Weight: 36845 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Maturity onset diabetes of the young, Type II diabetes mellitus