LRSAM1 (N-term) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
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Recommended Dilution | Western Blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LRSAM1 |
Specificity | This antibody recognizes Human and Mouse LRSAM1 (N-term). Cellular Location: Cytoplasm. Note - Displays a punctuate distribution and localizes to a submembranal ring. Tissue Location: Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue. |
Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | leucine rich repeat and sterile alpha motif containing 1 |
Database Link | |
Background | LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al., 2003 [PubMed 14635195]; Amit et al., 2004 [PubMed 15256501]). |
Synonyms | Tsg101-associated ligase, TAL |
Note | Molecular Weight: 83594 Da |
Reference Data | |
Protein Families | Druggable Genome |
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