LILRA2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52479PU-N

LILRA2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD85h / LILRA2 Antibody (Center) in NCI-H292, NCI-H460 and A549 cell line lysates (35ug/lane). This demonstrates the LILRA2 antibody detected the LILRA2 protein (arrow).

• 

  Flow cytometric analysis of A549 cells using CD85h / LILRA2 Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 62-81 amino acids from the Central region of Human CD85h / LILRA2
• Specificity: This antibody recognizes Human CD85h / LILRA2 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: leukocyte immunoglobulin like receptor A2
• Database Link:
  Entrez Gene 11027 Human
  UniProt ID Q8N149
• Background: Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.
• Synonyms: LILRA-2, ILT1, LIR7, LIR-7, ILT-1
• Note: Molecular Weight: 52992 Da