Leucyl tRNA synthetase (LARS) (N-term) Rabbit Polyclonal Antibody

SKU AP52444PU-N

Leucyl tRNA synthetase (LARS) (N-term) rabbit polyclonal antibody, Purified

Product Data

• Application: FC, WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 183-213 amino acids from the N-terminal region of Human LARS.
• Specificity: This antibody recognizes Human and Mouse LARS (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: leucyl-tRNA synthetase
• Database Link:
  Q9P2J5
• Background: This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known.
• Synonyms: LARS, KIAA1352, Leucyl-tRNA synthetase, cytoplasmic, EC=6.1.1.4, Leucine-tRNA ligase, LeuRS
• Note: Molecular Weight: 134466 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Aminoacyl-tRNA biosynthesis, leucine and isoleucine biosynthesis, Valine