KREMEN2 (Center) Rabbit Polyclonal Antibody

SKU AP52408PU-N

KREMEN2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1/1000.; Western Blot: 1/100 - 1/500.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2
• Specificity: This antibody reacts to KREMEN2.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: kringle containing transmembrane protein 2
• Database Link:
  Q8NCW0
• Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
• Synonyms: KREMEN2, KRM2, Dickkopf receptor 2
• Note: Molecular Weight: 48849 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane