Kinesin 5C (KIF5C) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western blotting: 1/100-1/500. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from Human KIF5C |
Specificity | This antibody is specific for Kif5C-2 |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Protein A Chromatography followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 109495 Da |
Gene Name | kinesin family member 5C |
Database Link | |
Background | Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain.There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression. |
Synonyms | KIF5C, KIAA0531, NKHC2, Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2 |
Reference Data | |
Protein Families | Druggable Genome |
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