KCNV2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52321PU-N

KCNV2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KCNV2 Antibody (C-term) in 293, K562, HepG2, Jurkat, ZR-75-1 cell line lysates (35ug/lane). This demonstrates the KCNV2 antibody detected the KCNV2 protein (arrow).

• 

  Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue reacted with KCNV2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 477-507 amino acids from the C-terminal region of human KCNV2
• Specificity: This antibody recognizes Human KCNV2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: potassium voltage-gated channel modifier subfamily V member 2
• Database Link:
  Entrez Gene 169522 Human
  UniProt ID Q8TDN2
• Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.
• Synonyms: KV11.1, Kv8.2
• Note: Molecular Weight: 62459 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane