Inhibin beta A (INHBA) (N-term) Rabbit Polyclonal Antibody

SKU AP52211PU-N

Inhibin beta A (INHBA) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution:
  ELISA: 1/1000.; Western blot: 1/1000. ; Immunohistochemistry on paraffin sections: 1/10 - 1/50.; Flow cytometry: 1/10 - 1/50.; Immunofluorescence: 1/10 - 1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the N-terminal region of human INHBA.
• Specificity: This antibody reacts to INHBA.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified fraction.; Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 47442 Da
• Gene Name: inhibin beta A subunit
• Database Link:
  P08476
• Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
• Synonyms: Activin beta-A chain, Erythroid differentiation protein, Activin A, Activin BA

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway