HYAL2 (C-term) Rabbit Polyclonal Antibody

SKU AP52134PU-N

HYAL2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/1000. ; Flow Cytometry: 1/10-1/50. ; Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of human HYAL2 / Hyaluronidase-2
• Specificity: This antibody recognizes Human HYAL2 / Hyaluronidase-2 (C-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: hyaluronoglucosaminidase 2
• Database Link:
  Q12891
• Background: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
• Synonyms: LUCA2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2
• Note: Molecular Weight: 53860 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways