TIP30 (HTATIP2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52126PU-N

TIP30 (HTATIP2) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HTATIP2 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the HTATIP2 antibody detected the HTATIP2 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with HTATIP2 Antibody (N-term), which was peroxidase conjugated to the secondary antibody and followed by AB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human HTATIP2.
• Specificity: This antibody recognizes Human HTATIP2 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: HIV-1 Tat interactive protein 2
• Database Link:
  Entrez Gene 10553 Human
  UniProt ID Q9BUP3
• Background: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
• Synonyms: Oxidoreductase HTATIP2, CC3, TIP30
• Note: Molecular Weight: 27049 Da