Repulsive Guidance Molecule C (HFE2) (Center) Rabbit Polyclonal Antibody

CAT#: AP52036PU-N

Repulsive Guidance Molecule C (HFE2) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HFE2 / Hemojuvelin Antibody (Center) in mouse heart tissue lysates (35ug/lane). HFE2 (arrow) was detected using the purified Pab.

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded skeletal muscle reacted with HFE2 / Hemojuvelin Antibody (Center), which was peroxidase conjugated to the secondary antibody and followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 141~170 amino acids from the Central region of Human HFE2 / Hemojuvelin
• Specificity: This antibody recognizes Human and Mouse HFE2 / Hemojuvelin (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: hemochromatosis type 2 (juvenile)
• Database Link:
  Entrez Gene 69585 MouseEntrez Gene 148738 Human
  UniProt ID Q6ZVN8
• Background: HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin.
• Synonyms: HJV, RGMC
• Note: Molecular Weight: 45080 Da

Reference Data

• Protein Families: Transmembrane