H2BFWT (Center) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 60-88 amino acids from the Central region of Human H2BFWT |
| Specificity | This antibody recognizes |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Protein A column, followed by peptide affinity purification |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | H2B histone family member W, testis specific |
| Database Link | |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility. |
| Synonyms | Histone H2B type W-T |
| Note | Molecular Weight: 19618 Da |
| Reference Data | |
| Protein Pathways | Systemic lupus erythematosus |
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