H2BFWT (Center) Rabbit Polyclonal Antibody

CAT#: AP51992PU-N

H2BFWT (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of H2BFWT Antibody (Center) in 293 cell line lysates (35ug/lane).This demonstrates the H2BFWT antibody detected the H2BFWT protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 60-88 amino acids from the Central region of Human H2BFWT
• Specificity: This antibody recognizes
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: H2B histone family member W, testis specific
• Database Link:
  Entrez Gene 158983 Human
  UniProt ID Q7Z2G1
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.
• Synonyms: Histone H2B type W-T
• Note: Molecular Weight: 19618 Da

Reference Data

• Protein Pathways: Systemic lupus erythematosus