GTSE1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51981PU-N

GTSE1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GTSE1 Antibody (C-term) in Hela cell line lysates (35ug/lane). GTSE1 (arrow) was detected using the purified Pab.

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue reacted with GTSE1 Antibody (C-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining.

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  Flow cytometric analysis of Hela cells using GTSE1 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 691~720 amino acids from the C-terminal region of human GTSE1
• Specificity: This antibody recognizes Human GTSE1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: G2 and S-phase expressed 1
• Database Link:
  Entrez Gene 51512 Human
  UniProt ID Q9NYZ3
• Background: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
• Synonyms: Protein B99 homolog, GTSE-1
• Note: Molecular Weight: 76615 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: p53 signaling pathway