Glutathione Reductase (GSR) (C-term) Rabbit Polyclonal Antibody

SKU AP51963PU-N

Glutathione Reductase (GSR) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50. ; Immunofluoresecnce: 1/10-1/50. ; Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human Glutathione reductase.
• Specificity: This antibody recognizes Human Glutathione reductase (C-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: glutathione reductase
• Database Link:
  P00390
• Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
• Synonyms: GRase, GR, GSR, GLUR, GRD1
• Note: Molecular Weight: 56257 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism