NR3B (GRIN3B) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51956PU-N

NR3B (GRIN3B) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis ofGRIN3B Antibody (C-term) in A549 cell line lysates (35ug/lane).This demonstrates the GRIN3B antibody detected the GRIN3B protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with GRIN3B Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human GRIN3B
• Specificity: This antibody recognizes Human GRIN3B (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: glutamate ionotropic receptor NMDA type subunit 3B
• Database Link:
  Entrez Gene 116444 Human
  UniProt ID O60391
• Background: GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
• Synonyms: NMDAR3B, NR3B
• Note: Molecular Weight: 112992 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction