GPR17 (Center) Rabbit Polyclonal Antibody

SKU AP51923PU-N

GPR17 (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: This antibody is suitable for flow cytometry, immunohistochemistry on paraffin sections and Western blotting.; The suggested dilution is:; Flow cytometry: 1/10-1/50.; Immunohistochemistry on paraffin sections: 1/50-1/100.; Western blotting: 1/100-1/500.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 237-266aa) of human GPR17.
• Specificity: This antibody detects human GPR17.
• Buffer: PBS with 0.09% (W/V) Sodium Azide.; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: G protein-coupled receptor 17
• Database Link:
  Q13304
• Background: Members of the G protein coupled receptor (GPCR) superfamily contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The organization of the GPR17 gene differs from that of many other GPCRs in that the open reading frame is distributed on 2 exons; an additional exon contains the 5 prime untranslated region. Human GPR17 is expressed as 2.3 and 6.3 kb mRNAs exclusively in brain. The 2 transcripts appear to represent alternatively polyadenylated variants. Based on protein sequence homology and the conservation of certain key residues, GPR17 appears to be closely related to the P2Y family of GPCRs. There are two nemed isoforms.
• Synonyms: UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12
• Note: Molecular Weight: 40989 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane