GLDC (N-term) Rabbit Polyclonal Antibody

SKU AP51849PU-N

GLDC (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500.

• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 56~85 amino acids from the N-terminal region of Human GLDC
• Specificity: This antibody recpognizes Human and Mouse GLDC (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: glycine decarboxylase
• Database Link:
  P23378
• Background:
  Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
• Synonyms: GCSP, Glycine cleavage system P protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring), Glycine dehydrogenase (decarboxylating), mitochondrial
• Note: Molecular Weight: 112730 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycine, Metabolic pathways, serine and threonine metabolism