FSTL3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51732PU-N

FSTL3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in CEM cell line lysates (35ug/lane) using FSTL3 Antibody (C-term) Cat.-No AP51732PU-N. This demonstrates the FSTL3 antibody detected the FSTL3 protein (arrow).

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  Formalin fixed and paraffin embedded human testis tissue stained with FSTL3 Antibody (C-term) Cat.-No AP51732PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of FSTL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 228-258 amino acids from the C-terminal region of Human FSTL3
• Specificity: Recognizes Follistatin-related protein 3 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 27663 Da
• Gene Name: follistatin like 3
• Database Link:
  Entrez Gene 10272 Human
  UniProt ID O95633
• Background: FSTL3, follistatin-like 3, is a secreted glycoprotein of the follistatin-module-protein family. FSTL3 is expressed in the placenta and may play a role in regulating the extracellular matrix of the placenta. FSTL3 is a binding protein for activin and BMP2 and thought to regulate activin and myostatin during normal adult metabolic homeostasis. FSTL3 may also contribute to bone formation by inhibiting osteoclast differentiation from hematopoietic precursors. A chromosomal aberration involving FSTL3 is found in a case of B-cell chronic lymphocytic leukemia.
• Synonyms: Follistatin-like 3, Follistatin-related gene protein, FLRG, FSTL3

Reference Data

• Protein Families: Secreted Protein