FBXW12 (C-term) Rabbit Polyclonal Antibody

SKU AP51636PU-N

FBXW12 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50. ; Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of Human FBXW12
• Specificity: This antibody recognizes Human FBXW12 (C-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: F-box and WD repeat domain containing 12
• Database Link:
  Q6X9E4
• Background: Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM].
• Synonyms: FBW12, FBXO12, FBXO35, F-box only protein 35
• Note: Molecular Weight: 53056 Da

Reference Data

• Protein Families: Druggable Genome