ETS1 (N-term) Rabbit Polyclonal Antibody

SKU AP51470PU-N

ETS1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IF, WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50. ; Immunofluorescence: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of Human ETS1
• Specificity: This antibody recognizes Human ETS1 (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: ETS proto-oncogene 1, transcription factor
• Database Link:
  P14921
• Background: ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]).
• Synonyms: Protein C-ets-1, EWSR2, p54
• Note: Molecular Weight: 50408 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Dorso-ventral axis formation, Pathways in cancer, Renal cell carcinoma