Endothelin 1 (EDN1) (C-term) Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Immunofluorescence: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of Human EDN1 |
Specificity | This antibody recognizes Human Endothelin-1 (C-term). Other species not tested. |
Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | endothelin 1 |
Database Link | |
Background | The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms | PPET1, EDN1, ET1, HDLCQ7, EDN1 |
Note | Molecular Weight: 24425 Da |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Melanogenesis |
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