Cathepsin K (CTSK) (Center) Rabbit Polyclonal Antibody

SKU AP51131PU-N

Cathepsin K (CTSK) (Center) rabbit polyclonal antibody, Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/1000; Immunohistochemistry on Paraffin Sections: 1/10-1/50.; Flow Cytometry: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 96-126 amino acids from the Central region of Human Cathepsin K
• Specificity: This antibody recognizes Human Cathepsin K.
• Buffer: PBS; State: Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) Precipitation
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 36966 Da
• Gene Name: cathepsin K
• Database Link:
  P43235
• Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].
• Synonyms: Cathepsin O, Cathepsin X, Cathepsin O2, CTSK, CTSO, CTSO2

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome