delta 2 Catenin (CTNND2) (C-term) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | Peptide ELISA: 1/1000. Western Blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of Human CTNND2 |
Specificity | This antibody reacts to CTNND2. |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 132656 Da |
Gene Name | catenin delta 2 |
Database Link | |
Background | This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. |
Synonyms | CTNND2, NPRAP, Delta-catenin, Neurojungin, GT24 |
Reference Data | |
Protein Families | Druggable Genome |
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