CSAD (Center) Rabbit Polyclonal Antibody

CAT#: AP51094PU-N

CSAD (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CSAD Antibody (Center) western blot analysis in CEM, A549 cell line lysates (35ug/lane).This demonstrates the CSAD antibody detected the CSAD protein (arrow).

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  CSAD Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 204-234 amino acids from the Central region of human CSAD
• Specificity: This antibody reacts to human CSAD.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 55023 Da
• Gene Name: cysteine sulfinic acid decarboxylase
• Database Link:
  Entrez Gene 51380 Human
  UniProt ID Q9Y600
• Background: Cysteine sulfinic acid decarboxylase (CSAD) catalyses the penultimate and rate limiting step of taurine synthesis. Taurine is an amino sulphonic acid and is one of the most abundant amino acids in the brain. It has been found to be essential to a number of biological processes such as development of the brain and eye, reproduction, diabetes, osmoregulation as well as the anti-inflammatory activity of leukocytes.
• Synonyms: Sulfinoalanine decarboxylase, CSD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Taurine and hypotaurine metabolism