CROT (N-term) Rabbit Polyclonal Antibody
Product Data | |
Application | FC, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western blot: 1/50 - 1/100. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow cytometry: 1/10 - 1/50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 57~86 amino acids from the N-terminal region of human CROT |
Specificity | This antibody reacts to human and mouse CROT. |
Buffer | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 70178 Da |
Gene Name | carnitine O-octanoyltransferase |
Database Link | |
Background | CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. |
Synonyms | COT |
Reference Data | |
Protein Families | Druggable Genome |
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