COBRA1 (NELFB) (Center) Rabbit Polyclonal Antibody

SKU AP51000PU-N

COBRA1 (NELFB) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1/1000.; Western blot: 1/100 - 1/500.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 255-285 amino acids from the Central region of human COBRA1
• Specificity: This antibody reacts to COBRA1.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 65697 Da
• Gene Name: negative elongation factor complex member B
• Database Link:
  Q8WX92
• Background: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).
• Synonyms: Negative elongation factor B, COBRA1, KIAA1182, NELFB

Reference Data

• Protein Families: Transcription Factors