Claudin 22 (CLDN22) (Center) Rabbit Polyclonal Antibody

SKU AP50947PU-N

Claudin 22 (CLDN22) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, WB
• Recommended Dilution: ELISA: 1/1000.; Western blot: 1/100-1/500.; Flow Cytometry: 1/10-1/50.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CLDN22
• Specificity: This antibody recognizes CLDN22 (Center).
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 24509 Da
• Gene Name: claudin 22
• Database Link:
  Q8N7P3
• Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.
• Synonyms: Claudin-22

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction