AMCase (CHIA) (N-term) Rabbit Polyclonal Antibody

SKU AP50895PU-N

AMCase (CHIA) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, WB
• Recommended Dilution: Peptide ELISA: 1/1000.; Western blot: 1/100 - 1/500.; Flow cytometric: 1/10 - /50.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CHIA.
• Specificity: This antibody reacts to CHIA.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 52271 Da
• Gene Name: chitinase, acidic
• Database Link:
  Q9BZP6
• Background: CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
• Synonyms: Acidic mammalian chitinase, CHIA, TSA1902

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Amino sugar and nucleotide sugar metabolism