BCL3 (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | FC, IF, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western blotting: 1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/100. Flow Cytometry: 1/10-1/50. Immunofluorescence: 1/10-1/50. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 249~277 amino acids from the Center region of Human BCL3 |
Specificity | This antibody recognizes Bcl-3. |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Protein A Chromatography followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 46800 Da |
Gene Name | B-cell CLL/lymphoma 3 |
Database Link | |
Background | BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. |
Synonyms | BCL3, BCL4, D19S37 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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