ACTL7A (N-term) Rabbit Polyclonal Antibody

CAT#: AP50069PU-N

ACTL7A (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ACTL7A Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ACTL7A antibody detected the ACTL7A protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human ACTL7A
• Specificity: This antibody reacts to ACTL7A.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: actin like 7A
• Database Link:
  Entrez Gene 10881 Human
  UniProt ID Q9Y615
• Background: ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
• Synonyms: Actin-like-7-alpha
• Note: Molecular Weight: 48644 Da