Acrosin (ACR) (C-term) Rabbit Polyclonal Antibody

SKU AP50059PU-N

Acrosin (ACR) (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western blotting: 1/50-1/100.; Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 392~421 amino acids from the C-terminal region of Human ACR
• Specificity: This antibody recognizes Acrosin (C-term).
• Buffer: PBS; State: Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: acrosin
• Database Link:
  P10323
• Background: ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
• Synonyms: acrosin; ACRS; preproacrosin; proacrosin
• Note: Molecular Weight: 45847 Da

Reference Data

• Protein Families: Druggable Genome, Protease