ACCN1 (ASIC2) (Center) Rabbit Polyclonal Antibody

SKU AP50043PU-N

ACCN1 (ASIC2) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western blotting: 1/100 - 1/500.; Immunohistochemistry: 1/50 - 1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 127~156 amino acids from the Center region of human ACCN1
• Specificity: This antibody reacts to ASIC2 / ACCN1.
• Buffer: PBS containing 0.09% (W/V) sodium azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: acid sensing ion channel subunit 2
• Database Link:
  Q16515
• Background: ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
• Synonyms: BNAC1, MDEG, Brain sodium channel 1
• Note: Molecular Weight: 57709 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Taste transduction