ATP6AP1 (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | Western blotting (0.2 - 1 µg/ml) |
Reactivity | Canine, Equine, Human, Mouse, Rabbit, Rat |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide directed towards the middle region of human ATP6AP1 |
Buffer | State: Aff - Purified State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Purification | Purified using peptide immunoaffinity column |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | ATPase H+ transporting accessory protein 1 |
Database Link | |
Background | This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. |
Synonyms | V-ATPase subunit S1, Protein XAP-3, ATP6IP1, ATP6S1, VATPS1, XAP3 |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, Lysosome, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection |
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