14-3-3 sigma (SFN) (C-term) Rabbit Polyclonal Antibody

SKU AP33512PU-N

14-3-3 sigma (SFN) (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution: Western blotting: 1/1000.; Immunohistochemistry on Paraffin Sections: 1/10-1/50.; Flow Cytometry: 1/10-1/50.; Immunofluorescence: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of Human SFN.
• Specificity: This antibody recognizes Human SFN (C-term).; Other species not tested.
• Buffer: PBS; State: Purified; State: Liquid purified Ig fractioon; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 27774 Da
• Gene Name: stratifin
• Database Link:
  P31947
• Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axolly transported to the nerve termils. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of sigl transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in sigling pathways mediated by serine/threonine protein kises. Evidence indicates 14-3-3 is required for Raf 1 kise activity and phosphorylation among many other functions.
• Synonyms: Stratifin, HME1

Reference Data