GDNF Receptor alpha 2 (GFRA2) Chicken Polyclonal Antibody

SKU AP33456PU-N

GDNF Receptor alpha 2 (GFRA2) chicken polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IF, WB
• Recommended Dilution: ELISA: 1/128000-1/160000. ; Western blot: 1/5000-1/10000.; Immunofluorescence: 1/500-1/1000.
• Reactivity: Human
• Antibody Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: Recombinant His-tagged human GFRa-2 protein produced using CHO-based. ; For production of hGFRa-2, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. ; Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
• Specificity: This antibody detects Human GFRa-2 and doesn’t cross-react with hGFRa-1, hGFRa-3, hGFRa-4.; Other species not tested.
• Buffer: Concentrated Ammonium Sulphate in PBS pH 7.4; State: Aff - Purified; State: Liquid purified IgY fraction
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store at 2-8°C. ; As product is (NH4)₂SO₄ precipitate, mix well by pipetting or vortexing prior use.
• Stability: Shelf life: One year from despatch.
• Shipping: Blue Ice
• Gene Name: GDNF family receptor alpha 2
• Database Link:
  O00451
• Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).
• Synonyms: GFR-alpha-2, Neurturin receptor alpha, GDNF receptor beta, RET ligand 2, GDNFRB, RETL2, TRNR2

Reference Data