Proteasome subunit beta type 4 (PSMB4) Goat Polyclonal Antibody

SKU AP32717PU-N

Proteasome subunit beta type 4 (PSMB4) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC, WB
• Recommended Dilution: Peptide ELISA: 1/16000 (Detection Limit).; Western blot: 0.3-1.0 μg/ml. Approx 25kDa band observed in lysates of cell lines NIH3T3, HEK293, HeLa, Jurkat and K562. Primary incubation was 1 hour.; Immunohistochemistry on Paraffin Sections: 3.75 µg/ml (Human Skin).
• Reactivity: Bovine, Canine, Human, Mouse, Rabbit, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002787.2.
• Specificity: This antibody recognizes PSMB4.
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified IgG fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: proteasome subunit beta 4
• Database Link:
  P28070
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
• Synonyms: Proteasome subunit beta type-4, Proteasome beta chain, HsBPROS26, PROS-26, Macropain beta chain, Proteasome chain 3, HsN3
• Note: Calculated Molecular Weight (mature protein): 24.3kDa according to aa46-264 of NP_002787.2.

Reference Data