FANCE Goat Polyclonal Antibody

SKU AP31970PU-N

FANCE goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC
• Recommended Dilution:
  Peptide ELISA: 1/32000 (Detection limit). ; Western blot: Preliminary experiments gave an approx 70kDa band in Human Adipose and Uterus lysates after 0.1 µg/ml antibody staining. ; Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 58.7kDa according to NP_068741.1. The 70kDa band was successfully blocked by incubation with the immunizing peptide. ; Immunohistochemistry on Paraffin Sections: 3-6 μg/ml. In paraffin embedded Human Placenta shows nuclear staining in some trophoblasts.
• Reactivity: Bovine, Human
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of Human FANCE (NP_068741.1).
• Specificity: This antibody detects FANCE.
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified Ig fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: Fanconi anemia complementation group E
• Database Link:
  Q9HB96
• Background: FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.
• Synonyms: Fanconi anemia group E protein, FACE

Reference Data