Serotonin transporter (SLC6A4) (605-618) Goat Polyclonal Antibody

SKU AP31853PU-N

Serotonin transporter (SLC6A4) (605-618) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, FC, IF, WB
• Recommended Dilution:

  Peptide ELISA: 1/32000 (Detection Limit).; Western blot: 1-3 µg/ml. Approx 75kDa band observed in Mouse, Small Intestine lysates. ; Immunofluorescence: Strong expression of the protein seen in the Golgi apparatus/vesicles of HepG2 cells. Recommended concentration: 10µg/ml.; Flow Cytometry: Flow cytometric analysis of Jurkat cells. ; Recommended concentration: 10ug/ml.

• Reactivity: Bovine, Human, Mouse, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence, from the C-Terminus of the protein sequence according to NP_001036.1.
• Specificity: This antibody recognizes SLC6A4 (605-618).
• Buffer: Tris buffered saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: solute carrier family 6 member 4
• Database Link:
  P31645
• Background: SERT is a high affinity Na+, Cl- dependent transporter that clears serotonin from synaptic spaces to presynaptic neurons. It has been observed to migrate as 76kDa from rat brain, due to postranslational modifications other bands are observed from different tissues.
• Synonyms: 5HT transporter, 5HTT, HTT, Sodium-dependent serotonin transporter
• Note: Calculated Molecular Weight: 70.3kDa (Human NP_001036.1) and 70.0kDa (Mouse NP_034614.2).

Reference Data