KCNC3 (317-328) Goat Polyclonal Antibody

SKU AP31782PU-N

KCNC3 (317-328) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, WB
• Recommended Dilution: Peptide ELISA: 1/16000 (Detection Limit).; Western Blot: 0.3-1 µg/ml. Approx 80kDa band observed in Mouse and Rat Brain lysates.
• Reactivity: Human, Mouse, Porcine, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004968.2.
• Specificity: Recognizes KCNC3 / Kv3.3 (317-328).
• Buffer: Tris saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: potassium voltage-gated channel subfamily C member 3
• Database Link:
  Q14003
• Background: KCNC3 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.; The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
• Synonyms: Potassium voltage-gated channel subfamily C member 3, Voltage-gated potassium channel subunit Kv3.3, KSHIIID
• Note: Calculated Molecular Weight: 81.9kDa (Mouse NP_032448.2).

Reference Data