MMP11 (61-110) Rabbit Polyclonal Antibody

SKU AP31345PU-N

MMP11 (61-110) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/20000.; Immunofluorescence: 1/100 - 1/500.; Immunohistochemistry on Paraffin Sections: 1/100.; Western Blot: 1/500 - 1/1000.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human MMP-11 (aa61-110)
• Specificity: This antibody detects endogenous levels of total MMP-11 protein (aa61-110).
• Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol; State: Aff - Purified; State: Liquid purified IgG fraction
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: matrix metallopeptidase 11
• Database Link:
  P24347
• Background: MMP11, also known as stromelysin 3, is overexpressed in the stromal cells of invasive breast carcinomas but not in the stromal cells surrounding benign breast fibroadenomas. MMP11 is secreted in its proenzyme from and the zymogen has a mass of 64 kDa. The enzyme is rapidly activated to a 58 kDa form, a 45-47 kDa size, then to a 28 kDa final active form. MMP11 is not constitutively produced by most cell types. It has been found in lung fibroblasts and gingival fibroblasts when stimulated with EGF, as well as breast tumor and osteocarcinoma cell lines.
• Synonyms: MMP11, Stromelysin-3, SL-3, ST3, STMY3, Matrix metalloproteinase-11

Reference Data

• Protein Families: Druggable Genome, Protease