NLRC5 (N-term) Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, IHC, WB |
---|---|
Recommended Dilution | ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 2 µg/ml. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated |
Specificity | Human NLRC5 |
Buffer | PBS containing 0.02% Sodium as preservative State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | NLR family, CARD domain containing 5 |
Database Link | |
Background | NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-?B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer. |
Synonyms | NOD27, NOD4, Caterpiller protein 16.1, CLR16.1 |
Reference Data |
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