TRIP (TRAIP) (C-term) Goat Polyclonal Antibody

SKU AP31057PU-N

TRIP (TRAIP) (C-term) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC, WB
• Recommended Dilution: Peptide ELISA: 1/1000 (Detection Limit). ; Western Blot: 2.0 µg/ml. Approx.50kDa band observed in Human Testis lysates. ; An additonal band of unkown identity was also concistently observeved at 38kDa. This band was successfully blocked by incubation with the immunizing peptide. ; Immunohistochemistry on Paraffin Sections: 4-6 µg/ml. In paraffin embedded Human Spleen shows perinucxlear and textured cystoplasmic staining in selective areas.
• Reactivity: Human
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the C-Terminus of the protein sequence according to NP_005870.2.
• Specificity: This antibody detects TRIP / TRAIP
• Buffer: Tris saline, pH 7.3; State: Aff - Purified; State: Liquid purified IgG fraction.; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 53.3 kDa (NP_005870.2).
• Gene Name: TRAF interacting protein
• Database Link:
  Q9BWF2
• Background: TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
• Synonyms: TRIP, TRAF-interacting protein

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency