Maged1 (C-term) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western blot: 1:500 - 1:1000. |
| Reactivity | Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence derived from Mouse Melanoma-associated antigen D1. |
| Specificity | This antibody detects endogenous level of total Melanoma-associated antigen D1 protein. |
| Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Affinity-chromatography using epitope-specific peptide |
| Conjugation | Unconjugated |
| Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | melanoma antigen, family D, 1 |
| Database Link | |
| Background | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation. |
| Synonyms | Melanoma-associated antigen D1, MAGED1, NRAGE |
| Note | Molecular weight: 95 kDa |
| Reference Data | |
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