PPAR delta (PPARD) (430-441) Goat Polyclonal Antibody
Product Data | |
Application | ELISA, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/16000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. Western Blot: 0.3 - 1 µg/ml. |
Reactivity | Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Zebrafish |
Antibody Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from the C-terminus of human PPARD |
Specificity | This antibody detects PPAR-delta (C-term). It is expected to recognise isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_803184) with a different C-terminus. |
Buffer | Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Immunoaffinity chromatography |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | peroxisome proliferator activated receptor delta |
Database Link | |
Background | Peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta), a NR1 Thyroid Hormone-Like Receptor, is involved in the regulation of acyl-CoA synthetase 2 expression, lipid metabolism, embryo development, implantation, decidualization, and bone formation. PPAR beta/delta has been identified as a negative target of the APC gene and has been linked to colon cancer. |
Synonyms | PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Pathways in cancer, PPAR signaling pathway, Wnt signaling pathway |
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